New Hope For Celiac Treatment As Testing Continues For Nexvax2

Dr. Deanna Lites
November 07, 2018 - 5:18 pm

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DETROIT (WWJ) - Could wheat or rye bread be on the menu in the future for those who suffer from celiac disease?

A vaccine is in the works to treat the disease says WWJ health reporter Dr. Deanna Lites.

About one in a hundred people have celiac disease in the world. The signs and the symptoms of celiac disease can vary greatly and are different in children and adults ... but symptoms can include abdominal upset and fatigue. According to the Mayo Clinic if you have celiac disease, eating gluten triggers an immune response in your small intestine. Over time, this reaction damages your small intestine's lining and prevents absorption of some nutrients (malabsorption). The intestinal damage often causes diarrhea, fatigue, weight loss, bloating and anemia, and can lead to serious complications.

Right now, the treatment for celiac disease is to follow a gluten-free diet. But in the future, a vaccine called Nexvax2 may stop that inflammation so people with celiac disease can eat gluten.

Dr. Jennifer Appleyard is an allergist with Ascension St. John Hospital.

"Ninety percent of the people who have true celiac disease should benefit from this medication," says Appleyard. 

Nexvax 2 has moved into the second phase of testing.

The company is looking to enroll around 150 patients from around the world including the U.S.

To learn more about taking part in the study check out CLINICAL TRIALS